Enhanced retinal vasculature imaging with a rapidly configurable aperture

In adaptive optics scanning laser ophthalmoscope (AOSLO) systems, capturing multiply scattered light can increase the contrast of the retinal microvasculature structure, cone inner segments, and retinal ganglion cells. Current systems generally use either a split detector or offset aperture approach to collect this light. We tested the ability of a spatial light modulator (SLM) as a rapidly configurable aperture to use more complex shapes to enhance the contrast of retinal structure. Particularly, we varied the orientation of a split detector aperture and explored the use of a more complex shape, the half annulus, to enhance the contrast of the retinal vasculature. We used the new approach to investigate the influence of scattering distance and orientation on vascular imaging.


Publication Date:
Feb 23 2018
Date Submitted:
Jul 01 2019
Pagination:
1323-1333
Citation:
Biomedical optics express
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 Record created 2019-07-01, last modified 2019-08-05


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