The use of neurophysiological tools in the information systems domain has received increased attention over the last decade. The Hawaii International Conference on System Sciences has helped provide a home for rigorously exploring such work through related minitracks and symposia. This paper reports on a panel presented at the 49th HICSS conference held in 2016 during a symposium organized to help orient interested researchers to the usefulness of cognitive neuroscience in IS research. This paper first introduces the rise in the IS discipline for integrating the methodologies and tools of cognitive neuroscience. It then presents individual viewpoints from the varying panel members at the symposium as they addressed questions of longevity, applicability, and next steps for the neuroIS subdiscipline. The four panel members included Alan Dennis, Angelika Dimoka, Allen Lee, and Ofir Turel.